%0 Journal Article %T A small-molecule Fenton reagent for self-augmented chemodynamic therapy by intelligently regulating intracellular acidosis. %A Wang K %A Liu X %A Jia Y %A Pan L %A Shi M %A Pan W %A Li N %A Tang B %J Chem Commun (Camb) %V 60 %N 36 %D 2024 Apr 30 %M 38602162 %F 6.065 %R 10.1039/d4cc00760c %X A small-molecule Fenton reagent, integrating ferrocene with a carbonic anhydrase inhibitor, was designed to intelligently regulate intracellular acidosis for self-augmented chemodynamic therapy. Acidosis coupled with up-regulated ROS levels demonstrated potent cytotoxicity and effective tumor suppression.