%0 Journal Article
%T High Efficacy of Ivermectin for Strongyloidiasis Treatment.
%A Sengthong C
%A Pinlaor S
%A Yingklang M
%A Haonon O
%A Jantawong C
%A Pinlaor P
%A Sithithaworn P
%A Hongsrichan N
%J Am J Trop Med Hyg
%V 110
%N 5
%D 2024 May 1
%M 38579698
%F 3.707
%R 10.4269/ajtmh.23-0645
%X Infection with Strongyloides stercoralis is often asymptomatic but can be life-threatening in immunocompromised patients, which can be prevented by ivermectin (IVM) treatment. The efficacy of IVM has been reported to have lessened over time in some regions as a consequence of prolonged use and mass treatment campaigns. Ivermectin has been used in Thailand for more than a decade; therefore, we investigated the efficacy of a single dose (200 µg/kg) of IVM against in asymptomatic strongyloidiasis in northeastern Thailand. Fecal samples were collected before and 2 weeks after treatment and were analyzed for the presence of Strongyloides using a modified agar plate culture and the formalin-ethyl acetate concentration technique. Our results showed that single-dose IVM treatment successfully eliminated S. stercoralis infection in asymptomatic individuals in the endemic area with a 100% cure rate, indicating the high efficacy of IVM treatment in strongyloidiasis in northeast Thailand.