%0 Multicenter Study
%T Clinical manifestation, lifestyle, and treatment patterns of chronic erosive gastritis: A multicenter real-world study in China.
%A Yang YY
%A Li KM
%A Xu GF
%A Wang CD
%A Xiong H
%A Wang XZ
%A Wang CH
%A Zhang BY
%A Jiang HX
%A Sun J
%A Xu Y
%A Zhang LJ
%A Zheng HX
%A Xing XB
%A Wang LJ
%A Zuo XL
%A Ding SG
%A Lin R
%A Chen CX
%A Wang XW
%A Li JN
%J World J Gastroenterol
%V 30
%N 9
%D 2024 Mar 7
%M 38577179
%F 5.374
%R 10.3748/wjg.v30.i9.1108
%X <B>BACKGROUND: </B>Although chronic erosive gastritis (CEG) is common, its clinical characteristics have not been fully elucidated. The lack of consensus regarding its treatment has resulted in varied treatment regimens.<BR><B>OBJECTIVE: </B>To explore the clinical characteristics, treatment patterns, and short-term outcomes in CEG patients in China.<BR><B>METHODS: </B>We recruited patients with chronic non-atrophic or mild-to-moderate atrophic gastritis with erosion based on endoscopy and pathology. Patients and treating physicians completed a questionnaire regarding history, endoscopic findings, and treatment plans as well as a follow-up questionnaire to investigate changes in symptoms after 4 wk of treatment.<BR><B>RESULTS: </B>Three thousand five hundred sixty-three patients from 42 centers across 24 cities in China were included. Epigastric pain (68.0%), abdominal distension (62.6%), and postprandial fullness (47.5%) were the most common presenting symptoms. Gastritis was classified as chronic non-atrophic in 69.9% of patients. Among those with erosive lesions, 72.1% of patients had lesions in the antrum, 51.0% had multiple lesions, and 67.3% had superficial flat lesions. In patients with epigastric pain, the combination of a mucosal protective agent (MPA) and proton pump inhibitor was more effective. For those with postprandial fullness, acid regurgitation, early satiety, or nausea, a MPA appeared more promising.<BR><B>CONCLUSIONS: </B>CEG is a multifactorial disease which is common in Asian patients and has non-specific symptoms. Gastroscopy may play a major role in its detection and diagnosis. Treatment should be individualized based on symptom profile.