%0 Journal Article
%T Electroretinography in congenital nystagmus patients with a normal fundus examination.
%A Rhiu S
%A Chang JH
%A Park TK
%A Lee YW
%A Lee JB
%A Youn I
%A Han SY
%J Jpn J Ophthalmol
%V 68
%N 3
%D 2024 May 3
%M 38568447
%F 2.211
%R 10.1007/s10384-024-01058-2
%X <B>OBJECTIVE: </B>To identify the ophthalmic causes of congenital nystagmus with normal eye examination by electroretinography (ERG).<BR><B>METHODS: </B>Retrospective observational study.<BR><B>METHODS: </B>We reviewed the medical records of patients younger than 6 months of age who presented between June 2008 and November 2011 with nystagmus and no other neurological signs following an otherwise normal eye examination. A complete ophthalmic examination and ERG (Nicolet Bravo system; Nicolet Biomedial & RETIscan; Roland Instruments), fundus photography, and Ishihara color test were performed to identify any ophthalmic causes of congenital nystagmus.<BR><B>RESULTS: </B>Thirty-three patients met the criteria. Rod dysfunction was diagnosed in 4 patients (12.1%), cone dysfunction in 2 patients (6.1%), and cone-rod dysfunction in 1 patient (3.0%). The results of ERG were negative in 2 patients (6.1%). Idiopathic infantile nystagmus was diagnosed in the remaining 24 patients (72.7%) based on their normal ERG examination.<BR><B>CONCLUSIONS: </B>In Korean congenital nystagmus patients with a normal fundus examination, achromatopsia and Leber's congenital amaurosis are uncommon causes. ERG is needed to make a definite diagnosis and provide prognostic information in congenital idiopathic nystagmus patients with a normal fundus examination.