%0 Case Reports
%T Plexiform neurofibroma masquerading as a giant congenital melanocytic nevus.
%A Olsen GM
%A Siegel DH
%A Sokumbi O
%A Chiu YE
%J Pediatr Dermatol
%V 0
%N 0
%D 2024 Apr 1
%M 38561464
%F 1.997
%R 10.1111/pde.15611
%X A 4-month-old male presented for a large, hypertrichotic brown patch on the upper back with several scattered 0.5-1.5 cm, round to oval, brown macules and patches on the trunk and extremities. The lesion was initially diagnosed as a giant congenital melanocytic nevus based on clinical exam and histopathology with immunohistochemical stains. The patient was later diagnosed with neurofibromatosis type 1, and the lesion on the back developed a "bag of worms" texture consistent with a plexiform neurofibroma and found to harbor a pathogenic variant in the NF1 gene. This case highlights the diagnostic challenge of differentiating these lesions and their overlapping clinical and histopathological features.