%0 Journal Article
%T Tumor-like Lesions in Primary Angiitis of the Central Nervous System: The Role of Magnetic Resonance Imaging in Differential Diagnosis.
%A Zedde M
%A Napoli M
%A Moratti C
%A Pavone C
%A Bonacini L
%A Di Cecco G
%A D'Aniello S
%A Grisendi I
%A Assenza F
%A Boulouis G
%A Nguyen TN
%A Valzania F
%A Pascarella R
%J Diagnostics (Basel)
%V 14
%N 6
%D 2024 Mar 14
%M 38535038
%F 3.992
%R 10.3390/diagnostics14060618
%X Primary Angiitis of the Central Nervous System (PACNS) is a rare disease and its diagnosis is a challenge for several reasons, including the lack of specificity of the main findings highlighted in the current diagnostic criteria. Among the neuroimaging pattern of PACNS, a tumefactive form (t-PACNS) is a rare subtype and its differential diagnosis mainly relies on neuroimaging. Tumor-like mass lesions in the brain are a heterogeneous category including tumors (in particular, primary brain tumors such as glial tumors and lymphoma), inflammatory (e.g., t-PACNS, tumefactive demyelinating lesions, and neurosarcoidosis), and infectious diseases (e.g., neurotoxoplasmosis). In this review, the main features of t-PACNS are addressed and the main differential diagnoses from a neuroimaging perspective (mainly Magnetic Resonance Imaging-MRI-techniques) are described, including conventional and advanced MRI.