%0 Case Reports
%T Use of Baricitinib in a patient with treatment-resistant pyoderma gangrenosum.
%A Bechard K
%A Gniadecki R
%J SAGE Open Med Case Rep
%V 12
%N 0
%D 2024
%M 38524384
暂无%R 10.1177/2050313X241235444
%X Pyoderma gangrenosum is a rare inflammatory neutrophilic disorder with no uniformly effective therapy and limited high-level evidence. Common therapies include immunosuppressive and immunomodulating agents. There exist several case series using small molecules as treatment modalities. Here, we report a case of a 78-year-old female with a diagnosis of pyoderma gangrenosum and metastatic high-grade serous carcinoma of the ovary who was treated with Baricitinib 4 mg daily in combination with a tapering course of prednisone after failing other conventional therapies including systemic corticosteroids, colchicine, and intravenous immunoglobulin.