%0 Journal Article
%T Clinical practicality and patient performance for surface-guided automated VMAT gating for DIBH breast cancer radiotherapy.
%A Huijskens S
%A Granton P
%A Fremeijer K
%A van Wanrooij C
%A Offereins-van Harten K
%A Schouwenaars-van den Beemd S
%A Hoogeman MS
%A Sattler MGA
%A Penninkhof J
%J Radiother Oncol
%V 195
%N 0
%D 2024 06 15
%M 38492672
%F 6.901
%R 10.1016/j.radonc.2024.110229
%X To evaluate the performance of automated surface-guided gating for left-sided breast cancer with DIBH and VMAT.<BR>Patients treated in the first year after introduction of DIBH with VMAT were retrospectively considered for analysis. With automated surface-guided gating the beam automatically switches on/off, if the surface region of interest moved in/out the gating tolerance (±3 mm, ±3°). Patients were coached to hold their breath as long as comfortably possible. Depending on the patient's preference, patients received audio instructions during treatment delivery. Real-time positional variations of the breast/chest wall surface with respect to the reference surface were collected, for all three orthogonal directions. The durations and number of DIBHs needed to complete dose delivery, and DIBH position variations were determined. To evaluate an optimal gating window threshold, smaller tolerances of ±2.5 mm, ±2.0 mm, and ±1.5 mm were simulated.<BR>525 fractions from 33 patients showed that median DIBH duration was 51 s (range: 30-121 s), and median 4 DIBHs per fraction were needed to complete VMAT dose delivery. Median intra-DIBH stability and intrafractional DIBH reproducibility approximated 1.0 mm in each direction. No large differences were found between patients who preferred to perform the DIBH procedure with (n = 21) and without audio-coaching (n = 12). Simulations demonstrated that gating window tolerances could be reduced from ±3.0 mm to ±2.0 mm, without affecting beam-on status.<BR>Independent of the use of audio-coaching, this study demonstrates that automated surface-guided gating with DIBH and VMAT proved highly efficient. Patients' DIBH performance far exceeded our expectations compared to earlier experiences and literature. Furthermore, gating window tolerances could be reduced.