%0 Journal Article
%T Novel MED15::ATF1 fusion in a pediatric melanoma with spitzoid features and aggressive presentation.
%A Furtado LV
%A Cardenas M
%A Santiago T
%A Ruiz RE
%A Shi Z
%A Pappo A
%A Kacar M
%J Genes Chromosomes Cancer
%V 63
%N 3
%D 2024 03
%M 38459940
%F 4.263
%R 10.1002/gcc.23230
%X Childhood melanoma is a rare and biologically heterogeneous pediatric malignancy. The differential diagnosis of pediatric melanoma is usually broad, including a wide variety of spindle cell or epithelioid neoplasms. Different molecular alterations affecting the MAPK and PI3K/AKT/mTOR pathways, tumor suppressor genes, and telomerase reactivation have been implicated in melanoma tumorigenesis and progression. Here, we report a novel MED15::ATF1 fusion in a pediatric melanoma with spitzoid features and an aggressive clinical course.