%0 Case Reports %T Tumor reduction after SARS‑CoV‑2 infection in a patient with lung cancer: A case report. %A Zhang X %A Chen J %A Sun J %A Gao S %A Zhao F %A Qian N %J Oncol Lett %V 27 %N 4 %D 2024 Apr %M 38455664 %F 3.111 %R 10.3892/ol.2024.14302 %X Lung cancer is one of the most common malignancies worldwide. Since the global outbreak of the coronavirus disease 2019 (COVID-19) pandemic in 2020, the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on lung cancer has been extensively studied. Despite reports about SARS-CoV-2 infection inducing a significant increase in the number of medical visits for patients with cancer, the virus has also been reported to produce some unknown benefits. The present study reports the case of a patient with lung cancer whose tumor lesion was reduced in size after SARS-CoV-2 infection even though the therapeutic regimen remained unchanged. Although the mechanism involved is not yet understood, this case supports the novel idea of applying SARS-CoV-2 in oncolytic virotherapy.