%0 Journal Article
%T Use of alloplastic implants for correction of deviated nasal septum: Systematic review and meta-analysis.
%A Jomah M
%A Smith O
%A Villemure-Poliquin N
%A Cunningham H
%J Am J Otolaryngol
%V 45
%N 3
%D 2024 May-Jun 28
%M 38447465
%F 2.873
%R 10.1016/j.amjoto.2024.104240
%X <B>OBJECTIVE: </B>To systematically reviews the safety and effectiveness of alloplastic implants (AI) in septoplasty.<BR><B>METHODS: </B>We conducted a comprehensive search in Medline, EMBASE, SCOPUS, CINAHL, and Cochrane Library databases to identify articles on septoplasty using AI. We also manually searched reference lists of included articles. Inclusion criteria involved prospective or retrospective case-series studies of adults with deviated nasal septum (DNS) who underwent septoplasty with AI, with sufficient follow-up data. Two authors independently screened articles, reviewed full manuscripts, and extracted data.<BR><B>RESULTS: </B>Out of 5370 articles, 16 met inclusion criteria, encompassing 884 patients from 14 eligible studies. Most studies had fair quality. AI materials included Polydioxanone (PDS), Polycaprolactone (PCL), Titanium, Macropore, and PolyMax. AI usage improved nasal obstruction in most patients, with 95.6 % (84.8 %-100 %) based on physical examination and 96.9 % (89.6 %-100 %) based on symptoms. AI-related complications occurred in 4.3 % (0 %-12.8 %) of cases, mostly non-serious.<BR><B>CONCLUSIONS: </B>AI use can be considered as a useful adjunct in septoplasty, with uncommon complications similar to standard procedures. However, due to limited-quality evidence, further prospective controlled studies are needed.