%0 Case Reports
%T Unsuccessful transscleral cyclophotocoagulation in oculocutaneous albinism.
%A Dotson AD
%A Fingert JH
%A Boese EA
%J Am J Ophthalmol Case Rep
%V 34
%N 0
%D 2024 Jun
%M 38404485
暂无%R 10.1016/j.ajoc.2024.102020
%X <B>UNASSIGNED: </B>To report a case of unsuccessful transscleral cyclophotocoagulation in a patient with OCA1A tyrosinase-negative oculocutaneous albinism.<BR><B>UNASSIGNED: </B>A 35-year-old Asian female with molecularly diagnosed OCA1A (tyrosinase-negative) oculocutaneous albinism and unilateral severe mixed mechanism glaucoma underwent transscleral cyclophotocoagulation on two separate occasions to treat elevated intraocular pressure. The intraocular pressure remained markedly elevated approximately 1 month following two separate treatments of transscleral cyclophotocoagulation while using high energy settings. The poor efficacy of both cyclophotocoagulation treatments was most likely due to a lack of melanin in the setting of oculocutaneous albinism.<BR><B>UNASSIGNED: </B>Cyclophotocoagulation in patients with oculocutaneous albinism is less likely to yield a desired lowering of intraocular pressure due to the absence of melanin.