%0 Multicenter Study
%T Pityriasis Rubra Pilaris: A Multicentric Case Series of 65 Spanish Patients.
%A Montero-Menárguez J
%A Amat Samaranch V
%A Puig Sanz L
%A Ruiz-Villaverde R
%A Arias-Santiago S
%A Larrea García M
%A Ruiz Genao D
%A Ferrán M
%A Schneller-Pavelescu L
%A Romero Ferreiro C
%A Rivera Díaz R
%J Actas Dermosifiliogr
%V 115
%N 8
%D 2024 Sep 22
%M 38401879
暂无%R 10.1016/j.ad.2024.02.019
%X <B>BACKGROUND: </B>PRP is a rare entity of unknown etiopathogenesis. Lack of management guidelines makes it a challenge for clinicians.<BR><B>OBJECTIVE: </B>To add our experience to increase evidence about PRP.<BR><B>METHODS: </B>We performed a retrospective, descriptive and multicentric study of 65 patients with PRP, being the largest European case series of patients with PRP.<BR><B>RESULTS: </B>PRP was more frequent in male patients with an average age of 51 years, but erythrodermic forms presented in older patients (average age 61 years). Six (75%) paediatric patients and ten (60%) non-erythrodermic adults controlled their disease with topical corticosteroids. On the contrary, 26 (68%) erythrodermic patients required biologic therapy as last and effective therapy line requiring an average of 6.5 months to achieve complete response.<BR><B>CONCLUSIONS: </B>Our study showed a statistical difference in terms of outcome and response to treatment between children or patients with limited disease and patients who develop erythroderma.