%0 Journal Article
%T Concordance between freehand SPECT and conventional scintigraphy for sentinel lymph node detection in breast cancer.
%A Esteban Hurtado Á
%A Orozco Cortés J
%A Cárcamo Ibarra P
%A López González U
%A Badenes Romero Á
%A Navas de la Cruz MÁ
%A Siscar Gelo C
%A Casas Calabuig L
%A Abreu Sánchez P
%A Mut Dólera T
%A Balaguer Muñoz D
%A Reyes Ojeda MD
%A Plancha Mansanet C
%A Caballero Calabuig E
%J Rev Esp Med Nucl Imagen Mol (Engl Ed)
%V 43
%N 2
%D 2024 Mar-Apr 20
%M 38387784
暂无%R 10.1016/j.remnie.2024.02.007
%X <B>BACKGROUND: </B>Freehand SPECT can be a useful imaging technique for preoperative planning of sentinel lymph node biopsy (SLNB) as it allows localization of the sentinel node by 3D and real-time tomographic imaging and determines its depth after a few minutes of scanning. The aim of the study was to evaluate the correlation between the number of detected SNs between freehand SPECT images and lymphoscintigraphy (LS).<BR><B>METHODS: </B>100 patients with a diagnosis of invasive breast cancer and no clinical evidence of lymph node involvement prospectively underwent SLNB. The preoperative study included freehand SPECT imaging at 15min after injection and LS imaging at 25 and 60-90min after injection (early and late). The observed agreement was analyzed and a concordance study was performed between the number of SNs detected with freehand SPECT and LS.<BR><B>RESULTS: </B>The observed agreement in the detection of SNs between freehand SPECT and early LS was 72%; between freehand SPECT and late LS was 85%; and between early and late LS was 87%. In the concordance study, there was moderate concordance between freehand SPECT and early LS (kappa coefficient: 0.42); moderate-high concordance between freehand SPECT and late LS (kappa coefficient: 0.60); and moderate-high concordance between early and late LS (kappa coefficient: 0.70), with no significant differences between them (p-value=0.16).<BR><B>CONCLUSIONS: </B>Freehand SPECT showed a moderate-high concordance with conventional imaging studies and could be a valid alternative for the presurgical study of SLNB in breast cancer.