%0 Journal Article
%T Evaluating Fourier-transform infrared spectroscopy with IR Biotyper as a faster and simpler method for investigating the sources of an outbreak of legionellosis.
%A Nakajima N
%A Jinnai M
%A Izumiyama S
%A Kuroki T
%J Eur J Clin Microbiol Infect Dis
%V 43
%N 5
%D 2024 May 20
%M 38379053
%F 5.103
%R 10.1007/s10096-024-04781-3
%X Fourier-transform infrared (FTIR) spectroscopy using the IR Biotyper and core genome single nucleotide polymorphism (cgSNP) analysis were performed on 12 Legionella isolates associated with an outbreak at a spa house in Kanagawa Prefecture, Japan, and 3 non-outbreak isolates. The discriminative power of FTIR spectroscopy for 48-h incubation conditions of L. pneumophila in this outbreak was lower than cgSNP-based typing but higher than serogroup typing. FTIR spectroscopy could screen outbreak isolates from a group of genetically related isolates and may be useful as an initial typing method in Legionella outbreak investigations.