%0 Randomized Controlled Trial
%T Effects of acupuncture on vision and visual function in children with anisometropic amblyopia.
%A Ma C
%A Jia J
%A Ye Y
%A Sun Y
%A Yan X
%J Zhongguo Zhen Jiu
%V 44
%N 2
%D 2024 Feb 12
%M 38373760
暂无%R 10.13703/j.0255-2930.20230313-0003
%X <B>OBJECTIVE: </B>To observe the clinical efficacy of Tiaoqi Tongjing Mingmu acupuncture (acupuncture for regulating qi, unblocking meridians and brightening eyes) combined with conventional treatment for anisometropic amblyopia children.<BR><B>METHODS: </B>A total of 76 children with monocular anisometropic amblyopia were randomized into an observation group (38 cases, 2 cases dropped out) and a control group (38 cases). The lens covering therapy was adopted in both groups. The conventional treatment i.e. red flash, grating and visual stimulation was given in the control group, 5 min for one item each time; on the basis of the treatment in the control group, acupuncture was applied at bilateral Jingming (BL 1), Cuanzhu (BL 2), Fengchi (GB 20) and Guangming (GB 37) in the observation group. Both groups were treated once every other day, 3 times a week for 4 weeks. Before and after treatment, the best corrected visual acuity, the latency and amplitude of P100 wave of pattern visual evoked potential (P-VEP), the diopter (spherical equivalent [SE]) were observed, the stereoacuity was measured by Titmus stereoscopic examination, and the clinical efficacy was evaluated in both groups.<BR><B>RESULTS: </B>Compared with those before treatment, the best corrected visual acuity improved (P<0.05), the latency of P-VEP P100 wave was shortened and the amplitude of P-VEP P100 wave was increased (P<0.05), and the SE and Titmus values were decreased (P<0.05) after treatment in both groups. After treatment, in the observation group, the best corrected visual acuity was higher (P<0.05), the latency of P-VEP P100 wave was shorter and the amplitude of P-VEP P100 wave was higher (P<0.05), SE and Titmus values were lower (P<0.05) than those in the control group. The total effective rate was 86.1% (31/36) in the observation group, which was superior to 65.8% (25/38) in the control group (P<0.05).<BR><B>CONCLUSIONS: </B>During the visual plasticity period, Tiaoqi Tongjing Mingmu acupuncture combined with conventional treatment can effectively improve the best corrected vision, diopter and stereoacuity in children with anisometropic amblyopia, and enhance the nerve conduction function from retina to visual cortex. Its effect is superior to that of simple conventional treatment.<BR>目的: 观察“调气通经明目”针刺联合常规疗法治疗儿童屈光参差性弱视的临床疗效。方法: 将76例屈光参差性单眼弱视患儿随机分为观察组（38例，脱落2例）和对照组（38例）。两组均予配镜遮盖治疗，对照组予常规治疗（红闪、光栅、视刺激），每次每项5 min；观察组在对照组治疗基础上，针刺双侧睛明、攒竹、风池、光明。两组均隔日1次，每周3次，共治疗4周。分别于治疗前后观察两组患儿最佳矫正视力、图形视觉诱发电位（P-VEP）P100波潜伏期及振幅、屈光度［等效球镜度数（SE）值］，采用Titmus立体视图检查近立体视锐度，并评定两组临床疗效。结果: 与治疗前比较，治疗后两组患儿最佳矫正视力提高（P<0.05），P-VEP P100波潜伏期缩短、振幅升高（P<0.05），SE值、Titmus值降低（P<0.05）；治疗后，观察组最佳矫正视力高于对照组（P<0.05），P-VEP P100波潜伏期短于对照组、振幅高于对照组（P<0.05），SE值、Titmus值低于对照组（P<0.05）。观察组总有效率为86.1%（31/36），高于对照组的65.8%（25/38，P<0.05）。结论: 在视觉可塑期内，“调气通经明目”针刺联合常规治疗可有效改善屈光参差性弱视患儿最佳矫正视力、屈光度和立体视锐度，增强视网膜至视皮层神经传导功能，疗效优于单纯常规治疗。.