%0 Journal Article
%T The prevalence of developmental defects of enamel in a cohort of adults with cystic fibrosis - A cross sectional study.
%A FionaO'Leary 
%A Coffey N
%A Burke FM
%A Roberts A
%A O'Regan P
%A Kirwan L
%A Plant B
%A Hayes M
%J J Dent
%V 144
%N 0
%D 2024 05 17
%M 38373520
%F 4.991
%R 10.1016/j.jdent.2024.104893
%X Cystic Fibrosis is an autosomal recessive condition. It is a multisystem disease treated with a broad range of pharmacological therapies, diet and nutrition, and physiotherapy. Previous studies suggest that people with cystic fibrosis have a higher prevalence of developmental defects of enamel which may place this population at a greater risk of developing oral diseases such as caries. The aim of this study was to assess a cohort of people with cystic fibrosis (PwCF) for the presence of developmental defects of enamel and compare the results with a control group of people without cystic fibrosis.<BR>A cross sectional study involving 92 participants with cystic fibrosis and 92 controls was conducted in Cork University Dental School & Hospital. All participants completed a detailed questionnaire prior to undergoing a full clinical examination. The Developmental Defect of Enamel Index was used as a measurement index. All data was statistically analysed with the help of statisticians from Cystic Fibrosis Registry of Ireland.<BR>64 % (n = 59) of PwCF had enamel defects compared to just 30 % (n = 28) of people without cystic fibrosis. The median number of teeth affected by enamel defects in the study group was 1.5, compared to 0 in the control group.<BR>In this study the cohort of PwCF had more enamel defects than people without CF. Further research is required to investigate the aetiology of these findings.<BR>Clinicians should be vigilant after teeth have erupted in PwCF as they may have an increased susceptibility to developmental defects of enamel.