%0 Review
%T Spontaneous regression of a giant uterine leiomyoma after delivery: a case report and literature review.
%A Zhu-Ge L
%A Bei Q
%A Pan W
%A Ni X
%J BMC Pregnancy Childbirth
%V 24
%N 1
%D 2024 Feb 10
%M 38341545
%F 3.105
%R 10.1186/s12884-024-06324-2
%X <B>BACKGROUND: </B>Uterine leiomyomas are hormone-dependent benign tumors and often begin to shrink after menopause due to the reduction in ovarian steroids. The influence of pregnancy on uterine leiomyomas size remains unclear. Here, we present a case of spontaneous regression of a giant uterine leiomyoma after delivery.<BR><B>METHODS: </B>A 40-year-old woman presented with multiple uterine leiomyomas, one of which is a giant uterine leiomyomas (approximately 8 cm in diameter) that gradually shrinked after delivery. At over two months postpartum, the large myometrial leiomyoma had transformed into a submucosal leiomyoma, and over 3 years postpartum, both the submucosal leiomyoma and multiple intramural leiomyomas completely regressed.<BR><B>CONCLUSIONS: </B>Spontaneous regression of a giant uterine leiomyom is rare after delivery. Considering uterine leiomyoma regression until over 3 year postpartum,we need to observe the regression of uterine fibroid for a longer time postpartum in the absence of fibroid related complications. In addition, it will provide new insights for treatment options of uterine leiomyomas in the future.