%0 Case Reports
%T Salivary gland secretory carcinoma presenting as a cervical soft tissue mass: a case report.
%A Mokhles P
%A Sadeghipour A
%A Babaheidarian P
%A Mohebbi S
%A Keshtpour Amlashi Z
%A Gharib MH
%A Ahmadi MS
%A Khastkhodaei Z
%J J Med Case Rep
%V 18
%N 1
%D 2024 Feb 5
%M 38311786
暂无%R 10.1186/s13256-024-04364-y
%X <B>BACKGROUND: </B>Secretory carcinoma (SC) has been described as a distinct salivary gland tumor in the fourth edition of the World Health Organization (WHO) classification of head and neck tumors. SC is generally considered as a slow-growing low-grade malignant tumor, while several cases have been reported with high-grade features, and even metastases in the literature up until now. In this article, a soft tissue SC case is discussed with high-grade microscopic features and neural invasion. A review of the salivary gland SC cases with aggressive behavior is also debated.<BR><B>METHODS: </B>A 65-year-old Caucasian man presented with a left neck mass for the past six months. The imaging studies demonstrated a very large cystic cervical mass (46 × 23 mm) with papillary projections in the anterolateral aspect of the left neck zone Vb. He underwent left radical neck dissection (level I-V) and was followed up for 12 months with the diagnosis of Secretory carcinoma.<BR><B>CONCLUSIONS: </B>Although SC generally has a good outcome, multiple recurrences and unusual metastases may occur, which should be considered by either the pathologists or clinicians.