%0 Journal Article
%T Chiral Truxene-Based Self-Assembled Cages: Triple Interlocking and Supramolecular Chirogenesis.
%A Séjourné S
%A Labrunie A
%A Dalinot C
%A Canevet D
%A Guechaichia R
%A Bou Zeid J
%A Benchohra A
%A Cauchy T
%A Brosseau A
%A Allain M
%A Chamignon C
%A Viger-Gravel J
%A Pintacuda G
%A Carré V
%A Aubriet F
%A Vanthuyne N
%A Sallé M
%A Goeb S
%J Angew Chem Int Ed Engl
%V 63
%N 15
%D 2024 Apr 8
%M 38284742
%F 16.823
%R 10.1002/anie.202400961
%X Incorporating chiral elements in host-guest systems currently attracts much attention because of the major impact such structures may have in a wide range of applications, from pharmaceuticals to materials science and beyond. Moreover, the development of multi-responsive and -functional systems is highly desirable since they offer numerous benefits. In this context, we describe herein the construction of a metal-driven self-assembled cage that associates a chiral truxene-based ligand and a bis-ruthenium complex. The maximum separation between both facing chiral units in the assembly is fixed by the intermetallic distance within the lateral bis-ruthenium complex (8.4 Å). The resulting chiral cavity was shown to encapsulate polyaromatic guest molecules, but also to afford a chiral triply interlocked [2]catenane structure. The formation of the latter occurs at high concentration, while its disassembly could be achieved by the addition of a planar achiral molecule. Interestingly the planar achiral molecule exhibits induced circular dichroism signature when trapped within the chiral cavity, thus demonstrating the ability of the cage to induce supramolecular chirogenesis.