%0 Systematic Review
%T Preserving the left colonic artery in radical sigmoid and rectal cancer surgery is feasible: A meta-analysis.
%A Wang X
%A Li J
%A Chen W
%A Yang Q
%J Medicine (Baltimore)
%V 103
%N 4
%D 2024 Jan 26
%M 38277569
%F 1.817
%R 10.1097/MD.0000000000037026
%X <B>BACKGROUND: </B>This study aims to investigate the safety and feasibility of preserving left colonic artery (LCA) in radical sigmoid and rectal cancer surgery.<BR><B>METHODS: </B>Relevant articles were systematically searched on the PubMed, Embase, and Cochrane Library. The quality of included studies was evaluated using the Cochrane Handbook. A meta-analysis was conducted to assess the surgical outcomes and oncological outcomes by RevMan 5.4 software.<BR><B>RESULTS: </B>Fifteen studies with a total of 5054 patients, including 2432 patients with LCA preservation and 2622 patients without LCA preservation, were included and analyzed in this study. The meta-analysis revealed that preserving LCA in radical surgery of sigmoid and rectal cancer has lower anastomotic leakage incidence (OR = 1.03, 95% confidence interval = 0.83-1.27, P < .0001). There were no significant differences in the operative time, intraoperative blood loss, number of dissected lymph nodes, postoperative complications as well as the oncological outcomes including systemic recurrence, local recurrence, 5-year overall survival rate, and 5-year disease-free survival rate.<BR><B>UNASSIGNED: </B>This pooled analysis showed that preserving the LCA is safe and feasible in radical sigmoid and rectal cancer surgery.