%0 Journal Article
%T Advances and opportunities in methods to study protein translation - A review.
%A Zhang D
%A Gao Y
%A Zhu L
%A Wang Y
%A Li P
%J Int J Biol Macromol
%V 259
%N 0
%D 2024 Feb 1
%M 38171441
%F 8.025
%R 10.1016/j.ijbiomac.2023.129150
%X It is generally believed that the regulation of gene expression involves protein translation occurring before RNA transcription. Therefore, it is crucial to investigate protein translation and its regulation. Recent advancements in biological sciences, particularly in the field of omics, have revolutionized protein translation research. These studies not only help characterize changes in protein translation during specific biological or pathological processes but also have significant implications in disease prevention and treatment. In this review, we summarize the latest methods in ribosome-based translation omics. We specifically focus on the application of fluorescence imaging technology and omics technology in studying overall protein translation. Additionally, we analyze the advantages, disadvantages, and application of these experimental methods, aiming to provide valuable insights and references to researchers studying translation.