%0 Case Reports
%T DRESS and Stevens-Johnson Syndrome Overlap Secondary to Allopurinol in a 50-Year-Old Man-A Diagnostic and Treatment Challenge: Case Report.
%A Martínez JD
%A Franco R
%A Sáenz LM
%A Alvarado AG
%A García JA
%A Delgado SM
%A Ionescu MA
%A Busilă C
%A Tatu AL
%J Life (Basel)
%V 13
%N 12
%D 2023 Nov 24
%M 38137852
%F 3.251
%R 10.3390/life13122251
%X Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a drug reaction commonly related to eosinophilia, from uncertain epidemiology, and without consensus for diagnosis and treatment globally. It presents a great challenge in its management and is characterized by fever, lymphadenopathy, skin rash, and multisystemic involvement. An aggressive and difficult-to-manage clinical case is presented in a 50-year-old man with chronic kidney disease due to diabetes mellitus type 2 and systemic arterial hypertension, who developed an unusual variant similar to DRESS and Stevens-Johnson syndrome (SJS) overlap secondary to allopurinol, with skin manifestations without eosinophilia, but fulfilling clinical and laboratory criteria for DRESS and SJS syndrome.