%0 Journal Article %T Experience With a Vancomycin-sparing Empiric Antibiotic Guideline for Late-onset Sepsis in a Level-4 Neonatal Intensive Care Unit. %A Dumont O %A Iacono D %A Jacob A %A Aggarwal A %A Hagmann SHF %J Pediatr Infect Dis J %V 43 %N 2 %D 2024 Feb 1 %M 38108378 %F 3.806 %R 10.1097/INF.0000000000004172 %X A vancomycin-sparing guideline for suspected late-onset sepsis helped reduce vancomycin usage in our level-4 neonatal intensive care unit. Significant reduction in overall vancomycin use, with its likely unit-wide beneficial downstream effects, may need to be measured against the rare case of methicillin-resistant Staphylococcus aureus infection and delayed effective therapy.