%0 Case Reports
%T Myelodysplasia cutis masquerading as granulomatous dermatitis.
%A Yi LG
%A Guerra R
%A Irwin L
%A Noland MM
%A Singh A
%A Gradecki S
%A Gru AA
%A Flowers RH
%J J Cutan Pathol
%V 51
%N 3
%D 2024 Mar 13
%M 38088468
%F 1.458
%R 10.1111/cup.14571
%X Myelodysplastic syndromes (MDS) are a group of clonal hematopoietic neoplasms resulting from mutations in stem cells. They carry a risk of transformation to acute myeloid leukemia. Cutaneous manifestations of MDS, including myelodysplasia cutis or infiltration by MDS tumor cells, are rare, but significantly associated with increased risk of progression to high-grade myeloid tumors. The clinical and histopathologic differential diagnosis for myelodysplasia cutis includes interstitial granulomatous dermatitis (IGD), a reactive granulomatous dermatitis (RGD) associated with systemic diseases including rheumatologic diseases, and hematologic malignancy like MDS. We report a patient with MDS who presented with myelodysplasia cutis masquerading as IGD both in a clinical and histopathological manner.