%0 Journal Article
%T Subjective Cognitive and Communicative Complaints and Health-Related Quality of Life in Parkinson's Disease with and without Mild Cognitive Impairment.
%A Jaramillo-Jimenez A
%A Bocanegra Y
%A Buriticá O
%A Pineda Salazar DA
%A Moreno Gómez L
%A Tobón Quintero CA
%A Aguirre-Acevedo DC
%A Sierra Castrillon M
%A Vasquez D
%A Velez-Hernandez JE
%A Borda MG
%A García-Cifuentes E
%A Aguillón DF
%A Madrigal-Zapata L
%A Aarsland D
%A Lopera F
%J Rev Colomb Psiquiatr (Engl Ed)
%V 52
%N 4
%D 2023 Oct-Dec
%M 38065663
暂无%R 10.1016/j.rcpeng.2023.11.004
%X BACKGROUND: Mild Cognitive Impairment (MCI) is common in Parkinson's Disease (PD). Few studies have compared the Health-Related Quality of Life (HRQoL) in patients with and without MCI due to PD (PD-MCI), and its correlation to patients' subjective cognitive and communicative difficulties has not been explored.
OBJECTIVE: We aimed to compare HRQoL in PD-MCI and PD without MCI (PD-nMCI), and explore its possible relationship to subjective cognitive and communicative complaints.
METHODS: We included 29 PD-nMCI and 11 PD-MCI patients. The HRQoL was assessed with the Parkinson's Disease Questionnaire-39 (PDQ-39): its Cognition dimension was used as a measure of subjective cognitive complaints, its Communication dimension for subjective communicative complaints, and the summary index (PDQ-39 SI) as an indicator of HRQoL. Non-parametric partial correlations between the Cognition and Communication dimensions, and the adjusted PDQ-39 SI were conducted.
RESULTS: PD-MCI patients had greater subjective cognitive and communicative complaints and worse HRQoL than PD-nMCI patients. In the PD-MCI group, both subjective cognitive and communicative complaints exhibited significant direct correlations with the adjusted HRQoL scores.
CONCLUSIONS: HRQoL seems to be affected in PD-MCI, and it might be influenced by greater subjective cognitive and communicative complaints. Including patient-reported outcome measures of HRQoL, and providing cognitive and speech rehabilitation, as well as psychotherapeutic strategies to face these deficits can enhance the patient-centred approach in PD.