%0 Case Reports
%T Progressive Ataxia and Palatal Tremor Is Not Associated with IgLON5 Antibodies: Results From Two Cases.
%A Mastrangelo A
%A Giannoccaro MP
%A Donadio V
%A Ricciardiello F
%A Di Laudo F
%A Palombo F
%A Liguori R
%A Rizzo G
%J Cerebellum
%V 23
%N 4
%D 2024 Aug 7
%M 38060151
%F 3.648
%R 10.1007/s12311-023-01647-w
%X Progressive ataxia and palatal tremor (PAPT) and anti-IgLON5 disease share possible clinical presentations. Furthermore, both have been associated to a tauopathy mainly affecting the brainstem. Nonetheless, anti-IgLON5 antibodies have never been tested in PAPT. We report on two PAPT cases without evidence of anti-IgLON5 antibodies in both CSF and serum. Despite common clinical and pathological characteristics, PAPT and IgLON5 disease are two distinct entities.