%0 Journal Article
%T The Role of Olive Tree Polyphenols In The Prevention of COVID-19: A Scoping Review Part 2.
%A Dhuli K
%A Micheletti C
%A Maltese PE
%A Tanzi B
%A Benedetti S
%A Tezzele S
%A Mareso C
%A Connelly ST
%A Gaffuri F
%A Tartaglia GM
%A Nodari S
%A Arabia G
%A Fioretti F
%A Calandri C
%A Perrone MA
%A Bertelli M
%J Clin Ter
%V 174
%N 0
%D 2023 Nov-Dec
%M 37994758
暂无%R 10.7417/CT.2023.2481
%X The recent COVID-19 pandemic caused by SARS-CoV-2 affected hundreds of millions of people and caused millions of deaths. There are few effective medications against SARS-CoV-2, and several studies attempted to make drugs based on natural components, such as olive leaves. Olive leaves are rich in polyphenolic compounds, which were proposed as a viable co-therapy supplement to treat and improve clinical symptoms in COVID-19 patients. Polyphenols have renown anti-inflammatory and multitarget antiviral effects on several virus families, which could be among the reasons of the beneficial effects of the Mediterranean diet against COVID-19. This scoping review is focused on the effect of olive tree polyphenols as a natural remedy to inhibit SARS-CoV-2, mainly discussing their influence on the process of viral entry into host cells by endocytosis.