%0 Journal Article %T Consideration of vaping products as an alternative to adult smoking: a narrative review. %A Foster JA %J Subst Abuse Treat Prev Policy %V 18 %N 1 %D 2023 11 16 %M 37974269 %F 3.615 %R 10.1186/s13011-023-00571-w %X Tobacco harm reduction is a public health approach to reduce the impact of cigarette smoking on individuals. Non-combustible alternatives to cigarettes, such as electronic cigarettes (e-cigarettes), deliver nicotine to the user in the absence of combustion. The absence of combustion in e-cigarettes reduces the level of harmful or potentially harmful chemicals in the aerosol generated. This narrative review examines the published literature that studied the chemistry of e-cigarette aerosols, the related toxicology in cell culture and animal models, as well as clinical studies that investigated short- and long-term changes in biomarkers of smoke exposure after switching to e-cigarettes. In the context of the literature reviewed, the evidence supports the harm reduction potential for adult smokers who switch to e-cigarettes.