%0 Journal Article
%T In vitro manogepix susceptibility testing of South African Emergomyces africanus, Emergomyces pasteurianus, and Blastomyces emzantsi clinical isolates.
%A Nzimande SP
%A Govender NP
%A Maphanga TG
%J Antimicrob Agents Chemother
%V 67
%N 12
%D 2023 12 14
%M 37971237
%F 5.938
%R 10.1128/aac.01104-23
%X We performed in vitro antifungal susceptibility testing of manogepix against the yeast phase of 78 Emergomyces africanus, 2 Emergomyces pasteurianus, and 5 Blastomyces emzantsi isolates using a reference broth microdilution method following Clinical and Laboratory Standards Institute recommendations. All three pathogens had low minimum inhibitory concentrations ranging from <0.0005 to 0.008 mg/L. Manogepix should be investigated in animal models and potentially in future human clinical trials for endemic mycoses.