%0 Journal Article
%T Neuroimaging manifestations of paediatric histiocytoses.
%A Tan HEI
%A Lakshmanan R
%A Warne R
%A Walwyn T
%A Roebuck D
%J J Med Imaging Radiat Oncol
%V 0
%N 0
%D 2023 Nov 14
%M 37964685
%F 1.667
%R 10.1111/1754-9485.13602
%X Histiocytoses are rare multi-system disorders marked by abnormal histiocyte cell proliferation, affecting children with diverse clinical presentations. Classified into five groups in 2016, including Langerhans-related (L), cutaneous (C), malignant (M), Rosai-Dorfman disease (R) and haemophagocytic lymphohistiocytosis (H), newer entities such as ALK-positive histiocytosis have also emerged, heralding the era of molecular (sub)classification. Common entities include Langerhans cell histiocytosis (LCH), Erdheim-Chester disease (ECD), Rosai-Dorfman disease (RDD) and haemophagocytic lymphohistiocytosis (HLH). This pictorial essay aids radiologists in recognising and differentiating paediatric histiocytoses based on unique neuroimaging features.