%0 Journal Article
%T Global genomic diversity and conservation of SARS-CoV-2 since the COVID-19 outbreak.
%A Li H
%A Ding L
%A Liao R
%A Li N
%A Hong X
%A Jiang Z
%A Liu D
%J Microbiol Spectr
%V 11
%N 6
%D 2023 Dec 12
%M 37909759
%F 9.043
%R 10.1128/spectrum.02826-23
%X <B>OBJECTIVE: </B>Our results indicate that most severe acute respiratory syndrome coronavirus 2 genomes sampled from patients had a mutation rate ≤1.07 ‰ and genome-tail proteins (including S protein) were the main sources of genetic polymorphism. The analysis of the virus-host interaction network of genome-tail proteins showed that they shared some antiviral signaling pathways, especially the intracellular protein transport pathway.