%0 Journal Article
%T Using a time-varying LCAR-based strategy to investigate the spatiotemporal pattern of association between short-term exposure to particulate matter and COVID-19 incidence: a case study in the continental USA.
%A Liu S
%A Luo J
%A Dai X
%A Ji S
%A Lu D
%J Environ Sci Pollut Res Int
%V 30
%N 54
%D 2023 Nov 28
%M 37897578
%F 5.19
%R 10.1007/s11356-023-30621-6
%X Numerous studies have demonstrated that short-term exposure to particulate matter less than 10 μm (PM10) is positively associated with the COVID-19 incidence. However, no study has investigated the spatiotemporal pattern in this association, which plays important roles in identifying high-susceptibility regions and stages of epidemic. In this work, taking the 49 native states in America as an example, we used an advanced strategy to investigate this issue. First, time-series generalized additive model (GAM) were independently constructed to obtain the state-specific associations between short-term exposure to PM10 and the daily COVID-19 cases from 1 April 2020 to 31 December 2021. Then, a Leroux-prior-based conditional autoregression (LCAR) was used to spatially smoothen the associations. Third, the temporal variation of association and the reasons underlying the spatiotemporal heterogeneity were investigated by incorporating the time-varying GAM into LCAR. Results showed that PM10 was adversely associated with COVID-19 incidence in all the states. On average, a 10 μg/m3 increase of PM10 was associated with a 7.38% (95% CI 5.20-9.64%) increase in COVID-19 cases. A substantial spatial heterogeneity was observed, with strong associations in the middle and northeastern regions and weak associations in the western regions. The temporal trend of association presented a U shape, with the strongest association in the end of 2021. The vaccination rate was examined as a significant effect modifier. Our study provided the first evidence about the spatiotemporal pattern in PM10-COVID-19 associations and suggested that air pollution deserves more attention in the post-pandemic era and in the middle and northeastern regions in America for COVID-19 control and prevention.