%0 Journal Article
%T Diagnostic delay, comorbid hidradenitis suppurativa and the prognostic value of bacterial culture in folliculitis decalvans: A cohort study.
%A Lyakhovitsky A
%A Segal O
%A Galili E
%A Thompson CT
%A Tzanani I
%A Scope A
%A Baum S
%A Barzilai A
%J J Dtsch Dermatol Ges
%V 21
%N 12
%D 2023 12 24
%M 37875786
%F 5.231
%R 10.1111/ddg.15202
%X Folliculitis decalvans (FD) is a type of primary neutrophilic cicatricial alopecia often leading to irreversible hair loss. Data on its epidemiology, clinical features, outcomes, and prognostic factors are limited.<BR>To evaluate a cohort of patients with FD and identify characteristics of severe disease and prognostic factors which impede remission.<BR>This retrospective cohort study included 192 patients diagnosed with FD and followed for at least six months at a tertiary center between 2010 and 2020.<BR>There was a diagnostic delay averaging 22.2 (± 29.7) months. Comorbid follicular occlusion disorders were common. Bacterial cultures were positive in 45.6% of the cases, with Staphylococcus (S.) aureus being the most common pathogen. Severe disease was associated with comorbid hidradenitis suppurativa and a positive bacterial culture, particularly S. aureus. 50.7% of patients experienced complete remission: 32% within the first six months of treatment and 18.7% later during follow-up. Relapses were frequent. Negative prognostic factors for achieving remission included younger age and a positive bacterial culture.<BR>There is a need for the education of dermatologists to reduce the diagnostic delay. Screening FD patients for comorbid hidradenitis suppurativa and obtaining bacterial cultures is important for treatment planning.