%0 Journal Article
%T Haplosufficiency of MHCII in autoreactive germinal center B cells.
%A Fahlquist-Hagert C
%A Wittenborn TR
%A Ferapontov A
%A Jensen L
%A Terczyńska-Dyla E
%A Degn SE
%J Eur J Immunol
%V 54
%N 1
%D 2024 Jan 24
%M 37873698
%F 6.688
%R 10.1002/eji.202350422
%X Utilizing an autoimmune bone marrow chimera model we determined that B cells depend critically on MHCII expression for participation in the germinal center, but cells displaying a 50% reduction in surface MHCII compete efficiently with their wild-type counterparts. This provides insights into the requirements for germinal center participation.