%0 Journal Article
%T Dilemma in Differentiation of Spinocerebellar Ataxia Type 17 from Huntington's Disease：Comorbidity or Independent Disease?
%A Li A
%A Yao S
%A Liu J
%A Qi X
%A Duan F
%A Sun C
%J Int J Neurosci
%V 0
%N 0
%D 2023 Oct 19
%M 37855597
%F 2.59
%R 10.1080/00207454.2023.2273766
%X Both Huntington's disease (HD) and Spinocerebellar ataxia 17 (SCA17) mutations showed expanded CAG repeats, with overlapping clinical manifestation: motor disorders, psychiatric symptoms and cognitive impairments. Therefore, SCA17 is also called Huntington like disease (HD-like, HDL) type 4. In this paper, we reported that one patient had 47 CAG repeats in HTT gene and 42 CAG repeats in TBP gene. There is a dilemma in differentiation of SCA 17 from HD in one patient, never been reported before. Is the diagnosis comorbidity of HD with SCA17 or HD only?