%0 Journal Article
%T Head-to-Head Comparison of FDG and Radiolabeled FAPI PET: A Systematic Review of the Literature.
%A Guglielmo P
%A Alongi P
%A Baratto L
%A Abenavoli E
%A Buschiazzo A
%A Celesti G
%A Conte M
%A Filice R
%A Gorica J
%A Jonghi-Lavarini L
%A Lanzafame H
%A Laudicella R
%A Librando M
%A Linguanti F
%A Mattana F
%A Miceli A
%A Olivari L
%A Piscopo L
%A Romagnolo C
%A Santo G
%A Vento A
%A Volpe F
%A Evangelista L
%J Life (Basel)
%V 13
%N 9
%D 2023 Aug 28
%M 37763225
%F 3.251
%R 10.3390/life13091821
%X FAPI-based radiopharmaceuticals are a novel class of tracers, mainly used for PET imaging, which have demonstrated several advantages over [18F]FDG, especially in the case of low-grade or well-differentiated tumors. We conducted this systematic review to evaluate all the studies where a head-to-head comparison had been performed to explore the potential utility of FAPI tracers in clinical practice. FAPI-based radiopharmaceuticals have shown promising results globally, in particular in detecting peritoneal carcinomatosis, but studies with wider populations are needed to better understand all the advantages of these new radiopharmaceuticals.