%0 Journal Article
%T Differential Diagnosis and Therapeutic Advances in Multiple Myeloma: A Review Article.
%A Hussain M
%A Yellapragada S
%A Al Hadidi S
%J Blood Lymphat Cancer
%V 13
%N 0
%D 2023
%M 37731771
暂无%R 10.2147/BLCTT.S272703
%X Multiple myeloma (MM) is a hematologic malignancy characterized by the abnormal clonal proliferation of plasma cells that may result in focal bone lesions, renal failure, anemia, and/or hypercalcemia. Recently, the diagnosis and treatment of MM have evolved due to a better understanding of disease pathophysiology, improved risk stratification, and new treatments. The incorporation of new drugs, including proteasome inhibitors, immunomodulatory drugs, anti-CD38 antibodies and high-dose chemotherapy followed by hematopoietic stem cell transplantation, has resulted in a significant improvement in patient outcomes and QoL. In this review, we summarize differential diagnoses and therapeutic advances in MM.