%0 Journal Article %T Application of UV-C irradiation prevented a severe outbreak of proliferative kidney disease in rainbow trout aquaculture. %A Naas C %A Kappe A %A Schmidt-Posthaus H %A Lichtenecker M %J Dis Aquat Organ %V 155 %N 0 %D 2023 Aug 31 %M 37650481 %F 1.769 %R 10.3354/dao03744 %X There is an urgent need to establish protocols on how to protect salmonids in aquaculture from outbreaks of proliferative kidney disease (PKD). For this purpose, systems for a continuous application of peracetic acid (PAA, 0.1 mg l-1) and of ultraviolet C light (UV-C, 323.5-158.6 mW s cm-2) were installed in the inlet of raceway-channels within a sub-unit of a commercial rainbow trout Oncorhynchus mykiss farm. After 127 d of rearing, a fish health examination was conducted. Fish in the control and PAA treatment groups showed signs of PKD. In contrast, fish in the UV-C treatment group showed almost no signs of disease based on clinical examinations and necropsy. This observation indicates that UV-C irradiation could be a promising tool to protect fish from PKD in the future.