%0 Review
%T Living Donor-Initiated Domino Split-Liver Transplantation in Pediatric Setup: A Case Report With Literature Review.
%A Alim A
%A Karataş C
%A Akbulut A
%A Oğuz BH
%A Özden Ö
%A Emre Ş
%A Hoş G
%A Demir B
%A Kızılkan NU
%A Alper A
%A Kanmaz T
%J Transplant Proc
%V 55
%N 8
%D 2023 Oct 28
%M 37648577
%F 1.014
%R 10.1016/j.transproceed.2023.07.017
%X <B>BACKGROUND: </B>In patients undergoing liver transplantation for metabolic diseases, removing the patient's liver for transplantation to another recipient is called "domino liver transplantation." The extracted liver can be divided and transplanted into 2 recipients, which is called domino split-liver transplantation in the literature. However, in our study, the domino liver was obtained from a pediatric patient.<BR><B>METHODS: </B>A patient with maple syrup urine disease (MSUD) underwent a living donor liver transplant, and the explanted liver was divided in situ into right and left lobes and transplanted to 2 separate patients. Demographic data, surgical techniques, postoperative period, and patient follow-ups were evaluated.<BR><B>RESULTS: </B>The father's left lobe liver graft was transplanted into a 12-year-old boy with MSUD. The removed liver was divided in situ into right and left lobes. The left lobe was transplanted to a 14-year-old male patient, whereas the right lobe was transplanted to a 67-year-old male patient. The donor and the first recipient were discharged on postoperative days 5 and 22. The second pediatric patient who underwent domino split-left lobe transplantation was discharged on postoperative day 23. The adult patient who underwent domino split-right lobe transplantation died on postoperative day 12 owing to massive esophageal variceal bleeding.<BR><B>CONCLUSIONS: </B>Patients who underwent liver transplantation due to MSUD are among the best donor choices for domino liver transplantation. If the extracted liver has a sufficient volume and anatomic features for a split, it can be used in "selected cases."