%0 Case Reports
%T A Combination Therapy in a Rare Case of Adult-Onset Autoimmune Enteropathy.
%A Amer B
%A Khozaig WH
%A Alhadad MT
%A Abdelrahman N
%J Cureus
%V 15
%N 7
%D 2023 Jul
%M 37637519
暂无%R 10.7759/cureus.42538
%X Autoimmune enteropathy (AIE) is a differential diagnosis of incurable chronic diarrhea, malnutrition, and weight loss. This type of diarrhea is associated with protein enteropathy that usually affects the small intestine. The diagnosis of AIE is based on chronic diarrhea, malabsorption, specific histological result, antibodies against enterocytes, and excluding similar conditions. In this case, a 28-year-old female presented with diarrhea, lower limb edema, weight loss, and electrolyte imbalances. Endoscopic examination demonstrated duodenal villous atrophy, while duodenal biopsies revealed villous blunting, scattered intraepithelial lymphocytes, and crypt hyperplasia in the lamina propria. The patient was treated with immunosuppressive treatment including methylprednisolone and azathioprine, achieving clinical remission.