%0 Journal Article
%T New treatment insights into pancreatic acinar cell carcinoma: case report and literature review.
%A Zhao F
%A Yang D
%A Xu T
%A He J
%A Guo J
%A Li X
%J Front Oncol
%V 13
%N 0
%D 2023
%M 37465113
%F 5.738
%R 10.3389/fonc.2023.1210064
%X Pancreatic acinar cell carcinoma (PACC) is a rare pancreatic malignancy with unique clinical, molecular, and morphologic features. The long-term survival of patients with PACC is substantially better than that of patients with ductal adenocarcinoma of the pancreas. Surgical resection is considered the first choice for treatment; however, there is no standard treatment option for patients with inoperable disease. The patient with metastatic PACC reported herein survived for more than 5 years with various treatments including chemotherapy, radiotherapy, antiangiogenic therapy and combined immunotherapy.