%0 Journal Article
%T Clinical profile and outcome of surgical management of intramedullary spinal cord tumours: A single center study in a developing country.
%A Oyemolade TA
%A Balogun JA
%A Badejo OA
%A Malomo AO
%A Shokunbi MT
%A Idowu OK
%A Adeolu AA
%J World Neurosurg X
%V 20
%N 0
%D 2023 Oct
%M 37456686
暂无%R 10.1016/j.wnsx.2023.100228
%X <B>UNASSIGNED: </B>There is as yet a paucity of data on intramedullary spinal cord tumours (IMSCTs) in sub-Saharan Africa. This study aims to define the clinical profile and outcome of management of IMSCTs in a Nigerian tertiary hospital.<BR><B>UNASSIGNED: </B>This is a retrospective study of all the patients who had surgery for IMSCTs in our hospital over a 14 year period.<BR><B>UNASSIGNED: </B>There were 20 patients, 9 males, 11 females, in this study. The median age was 33 years (range = 7-78 years). The median duration of symptoms was 12 months (range = 1-120 months). Motor deficit was present in all but one (95%) of our patients. Only 25% of the patients presented in good functional status (McCormick grades I and II). The tumours were confined to the thoracic region in 10 patients (50%), while tumours in the thoracic region extending to the adjoining cervical and lumbar regions were seen in 6 patients (30%). Gross total tumour resection was achieved in 60% of the patients and subtotal resection in the remaining 40%. Astrocytoma and ependymoma were the most common tumours, each occurring in 35% of the cases. Six patients (30.0%) improved, 12 patients (60.0%) remained neurologically the same, while 2 patients (10.0%) deteriorated at the time of last follow up. The mortality rate was 15%. The preoperative functional status was a significant predictor of postoperative outcome (p = 0.03).<BR><B>UNASSIGNED: </B>Astrocytoma and ependymoma were the most common histological tumour types among our patients. Late presentation and poor pre-operative functional status were prominent features of our patients' cohort.