%0 Journal Article %T Lower Urinary Tract Obstruction in Newborns. %A Flores-Torres J %A Sanchez-Valle A %A Duncan JR %A Panzarino V %A Rodriguez JM %A Kirby RS %J Adv Pediatr %V 70 %N 1 %D 2023 08 %M 37422291 暂无%R 10.1016/j.yapd.2023.03.001 %X Lower urinary tract obstruction (LUTO) is a rare birth defect with a prevalence between 1 in 5,000 and 1 in 25,000 pregnancies. LUTO is one of the most common causes of congenital abnormalities of the renal tract. Several genetic conditions have been associated with LUTO. Most common causes of LUTO are posterior urethral valves and urethral atresia. Despite available prenatal and postnatal treatments, LUTO is a significant cause of morbidity and mortality in newborns causing significant end stage renal disease and pulmonary hypoplasia.