%0 Controlled Clinical Trial
%T Multiple Sustainable Benefits of a Rehabilitation Program in Therapeutic Management of Hypermobile Ehlers-Danlos Syndrome: A Prospective and Controlled Study at Short- and Medium-Term.
%A Hakimi A
%A Bergoin C
%A De Jesus A
%A Hoorelbeke A
%A Ramon P
%A Florea O
%A Fabre C
%A Mucci P
%J Arch Phys Med Rehabil
%V 104
%N 12
%D 2023 12 4
%M 37406924
%F 4.06
%R 10.1016/j.apmr.2023.06.012
%X To evaluate the effects of a 9-week rehabilitation program (RP) for patients with hypermobile Ehlers-Danlos syndrome (hEDS) in the short- and medium-term.<BR>Nonrandomized controlled trial with 6 months follow-up.<BR>Outpatient rehabilitation program.<BR>A referred sample of 36 hEDS patients were assessed for eligibility (N=36), 25 were included, 22 completed the RP and 19 completed the follow-up.<BR>A 9 -week control period without intervention followed by a 9-week RP.<BR>Functional exercise capacity was used as a primary outcome measure. Balance, kinesiophobia, fatigue, pain, quality of life, anxiety, depression, and hyperventilation were measured as secondary outcomes.<BR>No significant change was observed during the 9-week control period before the RP. There was a significant improvement immediately after the RP for the functional exercise capacity, balance with eyes closed, fatigue, and quality of life (P<.05). Even more improvements were found 6 weeks after the end of the RP, and there was still an improvement after 6 months in functional exercise capacity, kinesiophobia, depression, hyperventilation, and some components of the quality of life.<BR>This study supports the effectiveness of an RP as a useful management tool for hEDS patients.