%0 Case Reports %T Case report: Central venous catheter thrombosis complicated by chronic thromboembolic disease/pulmonary hypertension in two children requiring parenteral nutrition. %A Hanuna M %A Pattathu J %A Buech J %A Kamla C %A Kneidinger N %A Behr J %A Milger K %A Veit T %A Nagel M %A Abicht J %A Dalla-Pozza R %A Fischer M %A Jakob A %A Hermann M %A Schramm R %A Rosenthal LL %A Haas N %A Hörer J %A Hagl C %A Michel SG %J Front Cardiovasc Med %V 10 %N 0 %D 2023 %M 37363098 %F 5.846 %R 10.3389/fcvm.2023.1198204 %X Chronic thromboembolic pulmonary hypertension is a rare but life-threatening complication of long-term central venous catheters (CVC) in children. However, evidence in terms of potential treatment strategies and outcome data remains scarce. We describe two cases of CVC-related thrombosis (Hickman-catheter) complicated by recurrent pulmonary emboli. One patient experienced a complete thromboembolic obstruction of the right pulmonary artery with normal pulmonary pressures and the second patient suffered from a central thromboembolic obstruction of both pulmonary arteries associated with severe pulmonary hypertension. Both patients successfully underwent surgical thromboendarterectomy with deep hypothermic circulatory arrest.