%0 Journal Article
%T Association between interpregnancy interval and gestational diabetes mellitus: A cohort study of the National Vital Statistics System 2020.
%A Zhu X
%A Li W
%A Xi H
%A Li M
%J Int J Gynaecol Obstet
%V 164
%N 1
%D 2024 Jan 20
%M 37337776
%F 4.447
%R 10.1002/ijgo.14929
%X <B>OBJECTIVE: </B>To assess the association between interpregnancy interval (IPI) and gestational diabetes mellitus (GDM).<BR><B>METHODS: </B>Data of this retrospective cohort study were obtained from the National Vital Statistics System (NVSS) 2020. The participants were divided into different groups according to different IPI (<6, 6-11, 12-17, 18-23, 24-59 (reference), 60-119, ≥120 months). Multivariate logistic models were constructed to evaluate the association between IPI and GDM. Subgroup analysis was further performed.<BR><B>RESULTS: </B>A total of 1 515 263 women were included, with 123 951 (8.18%) having GDM. Compared with the 24-59 months group, the <6 months (odds ratio [OR] 0.64, 95% confidence interval [CI] 0.46-0.90, P = 0.009), 12-17 months (OR 0.96, 95% CI 0.94-0.98, P < 0.001), and 18-23 months (OR 0.94, 95% CI 0.93-0.96, P < 0.001) groups had a significantly lower risk of GDM, while the 60-119 months (OR 1.13, 95% CI 1.11-1.15, P < 0.001) and ≥120 months (OR 1.18, 95% CI 1.15-1.21, P < 0.001) groups had a significantly higher risk of GDM. No significant difference was observed in the risk of GDM between the 6-11 and 24-59 months groups (P = 0.542). The PI-GDM association varied across different groups of age, pre-pregnancy body mass index, pre-pregnancy smoking status, history of cesarean section, history of preterm birth, prior terminations, and parity.<BR><B>CONCLUSIONS: </B>An IPI of 18-23 months may be a better interval than 24-59 months in managing the risk of GDM.