%0 Systematic Review
%T Endemic Systemic Mycoses in Italy: A Systematic Review of Literature and a Practical Update.
%A Zerbato V
%A Di Bella S
%A Pol R
%A D'Aleo F
%A Angheben A
%A Farina C
%A Conte M
%A Luzzaro F
%A  
%A Luzzati R
%A Principe L
%J Mycopathologia
%V 188
%N 4
%D 2023 Aug 9
%M 37294504
%F 3.785
%R 10.1007/s11046-023-00735-z
%X Endemic systemic mycoses such as blastomycosis, coccidioidomycosis, histoplasmosis, talaromycosis, paracoccidioidomycosis are emerging as an important cause of morbidity and mortality worldwide. We conducted a systematic review on endemic systemic mycoses reported in Italy from 1914 to nowadays. We found out: 105 cases of histoplasmosis, 15 of paracoccidioidomycosis, 10 of coccidioidomycosis, 10 of blastomycosis and 3 of talaromycosis. Most cases have been reported in returning travelers and expatriates or immigrants. Thirtytwo patients did not have a story of traveling to an endemic area. Fortysix subjects had HIV/AIDS. Immunosuppression was the major risk factor for getting these infections and for severe outcomes. We provided an overview on microbiological characteristics and clinical management principles of systemic endemic mycoses with a focus on the cases reported in Italy.