%0 Review %T Radial Tunnel Syndrome: Review and Best Evidence. %A Wolf JM %A Patel R %A Ghosh K %J J Am Acad Orthop Surg %V 31 %N 15 %D 2023 Aug 1 %M 37276490 %F 4 %R 10.5435/JAAOS-D-23-00314 %X Radial tunnel syndrome (RTS) is caused by compression of the posterior interosseous nerve and consists of a constellation of symptoms that have previously been characterized as aspects of other disease processes, as opposed to a distinct diagnosis. First described in the mid-20th century as "radial pronator syndrome," knowledge regarding the anatomy and presentation of RTS has advanced markedly over the past several decades. However, there remains notable controversy and ongoing research regarding diagnostic imaging, nonsurgical treatment options, and indications for surgical intervention. In this review, we will discuss the anatomic considerations of RTS, relevant physical examination findings, potential diagnostic modalities, and outcomes of several treatment options.