%0 Journal Article %T Integration of Square Fiducial Markers in Patient-Specific Instrumentation and Their Applicability in Knee Surgery. %A León-Muñoz VJ %A Moya-Angeler J %A López-López M %A Lisón-Almagro AJ %A Martínez-Martínez F %A Santonja-Medina F %J J Pers Med %V 13 %N 5 %D 2023 Apr 25 %M 37240897 %F 3.508 %R 10.3390/jpm13050727 %X Computer technologies play a crucial role in orthopaedic surgery and are essential in personalising different treatments. Recent advances allow the usage of augmented reality (AR) for many orthopaedic procedures, which include different types of knee surgery. AR assigns the interaction between virtual environments and the physical world, allowing both to intermingle (AR superimposes information on real objects in real-time) through an optical device and allows personalising different processes for each patient. This article aims to describe the integration of fiducial markers in planning knee surgeries and to perform a narrative description of the latest publications on AR applications in knee surgery. Augmented reality-assisted knee surgery is an emerging set of techniques that can increase accuracy, efficiency, and safety and decrease the radiation exposure (in some surgical procedures, such as osteotomies) of other conventional methods. Initial clinical experience with AR projection based on ArUco-type artificial marker sensors has shown promising results and received positive operator feedback. Once initial clinical safety and efficacy have been demonstrated, the continued experience should be studied to validate this technology and generate further innovation in this rapidly evolving field.